Cone inputs to murine retinal ganglion cells

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Cone inputs to murine retinal ganglion cells

Responses of single retinal ganglion cells in different areas of mouse retina were studied to determine their cone inputs, using spectral sensitivity functions and chromatic adaptation. Spectral sensitivity curves were based on threshold response criteria to full field stimulation. The retina of the mouse was viewed through a dilated pupil with a surgical microscope. Ganglion cells were classif...

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Cone inputs to ganglion cells in hereditary retinal degeneration.

The photoreceptor layer degenerated, but cone nuclei apparently devoid of outer segments were retained in retinas of aged rats of the Royal College of Surgeons strain from which optic tract activity was recorded. Measures of sensitivity showed these single axons of retinal ganglion cells to have photopic spectral responses. Cone remnants containing a cone pigment may be the photoreceptive eleme...

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Specificity of cone inputs to macaque retinal ganglion cells.

The specificity of cone inputs to ganglion cells has implications for the development of retinal connections and the nature of information transmitted to higher areas of the brain. We introduce a rapid and precise method for measuring signs and magnitudes of cone inputs to visual neurons. Colors of stimuli are modulated around circumferences of three color planes in clockwise and counterclockwi...

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Nonlinear summation of M- and L-cone inputs to phasic retinal ganglion cells of the macaque.

We have studied the responses of ganglion cells in the macaque retina to stimuli that alternate in color. With most color combinations, the phasic retinal ganglion cells, which sum input from M- and L-cones in both center and surround, showed a response with twice the alternation frequency at equal luminance. This frequency doubling was directly related to the degree to which the M- and L-cones...

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Short-wavelength cone-opponent retinal ganglion cells in mammals.

In all of the mammalian species studied to date, the short-wavelength-sensitive (S) cones and the S-cone bipolar cells that receive their input are very similar, but the retinal ganglion cells that receive synapses from the S-cone bipolar cells appear to be quite different. Here, we review the literature on mammalian retinal ganglion cells that respond selectively to stimulation of S-cones and ...

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ژورنال

عنوان ژورنال: Vision Research

سال: 2000

ISSN: 0042-6989

DOI: 10.1016/s0042-6989(00)00122-x